The Smoking Gun
From Robert W. Malone:
CROSS-POST FROM NEPETALACTONE NEWSLETTER
Kevin has a remarkably clear, penetrating and mature mind. In this essay he addresses many of the recent “purity spiral” issues. It is not a hard read for the non-molecular biologist once you get beyond restriction endonucleases and a bit of inside baseball, and I suggest it is well worth your time and effort. –
Many moons ago I was on a podcast with Alex Washburn regarding his paper
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“Endonuclease Fingerprint indicates a synthetic origin of SARS-CoV-2”
This was the first data that really cemented the synthetic origins of SARs-CoV-2. The ZooCrew went into high gear with the typical smoke grenades and even published other fraudulent associations with the wet market to distract from this (Pekar, Worobey and Andersen to name just a few). Worobey has a history of covering up state leaks with HIV. Everyone is likely aware of Kristian Andersen’s sudden about-face with Fauci regarding his opinion on the synthetic origin of SARs-CoV-2 with the Proximal Origins paper. He went on to be awarded a healthy multi-million dollar grant for reconsidering his position and manifesting it in the Nature paper. These folks are conflicted and aggressive online. They behave very similar to Peter Hotez with his demands for military intervention against anti-vaxxers.
These antagonists were just delivered a final blow.
The argument that Bruttel et al. put forward was that SARs-CoV-2 was unique in its even distribution of certain enzyme cut sites that are commonly used with Golden Gate genome assembly strategies. I previously put together a substack on the nature of these interesting TypeIIs restriction enzymes that helps explain why they are such handy tools for generating scar-less or ‘no see-um’ synthetic genome assemblies.
The ZooCrew screamed “Coincidence“.
But now, Emily Kopp from The US Right to Know (USRTK) has obtained additional detail about the DEFUSE proposal that is far more than a smoking gun but ,in fact, is more analogous to finding the gun, fingerprint and confession note in one place.
Emily found evidence that this proposal also listed the very restriction enzyme (BsmBI) that Bruttel et al. claimed could build the virus. Not only did Bruttel et al. notice that BsmBI sites were conveniently evenly spaced throughout the viral genome and this spacing was not only NOT observed in other CVs but that this approach made complete sense as a logical path to manually assembling the genome.
Low and behold the DEFUSE proposal actually contains NEB R0580S part numbers to order these very enzymes to construct the virus in the manner Bruttel et al. predicted.
This is a case closed event!
There is no more debate. C19 was made in a lab. Which lab and when is still a hot topic but it didn’t come from a pangolin courting a bat.
Now, for the controversy you will see spill out into the twitterverse-
This is also the time where a fair number of Zero Sum Game zealots will beg you not to look at this data. There is trend in the community of freedom fighters to think they are in a zero sum attention competition, where anyone detracting from COVID being a scam is a controlled op agent that is distracting you with irrelevant fear porn.
I have some thoughts for these folks. Many of them I admire so I bring this to their attention as I’m anticipating plenty of backlash just for tweeting about this topic.
Nick sums this up with the most clarity. Nick is a high-integrity, stand-up guy. This is not roast of Nick and he has salient points on this topic. He most elegantly sums up a common position of these folks.
Scico 
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